Post-Partum Ovarian Vein Thrombosis: Combined Effect of Infection and Factor V Leiden Mutation

To the Editor, Ovarian vein thrombosis (OVT) is a rare complication of pregnancy that mainly affects women in their 3rd or 4th decade. Numerous etiologies have been proposed, including ones of idiopathic origin. Early therapy with anticoagulants can be lifesaving; hence, a high index of suspicion is important in order to avoid serious complications such as pulmonary embolism (14%), sepsis, and death [1]. In this letter, an attempt at uncovering one of the etiologies to further solidify our understanding of the disease is made. A 34-year-old female, gravida 3, para 3, presented on the fifth day after an uncomplicated normal vaginal delivery with right lower quadrant pain, fever, and chills. She had been diagnosed with Behçet’s disease 8 years ago and was maintained on colchicine and steroids for 2 years, which were stopped later. The patient denied previous episodes of deep vein thrombosis (DVT), as well as family history of hypercoagulable diseases. The course of her pregnancy was uneventful except for a positive rectovaginal culture for beta-hemolytic group B streptococci, for which she received Post-Partum Ovarian Vein Thrombosis: Combined Effect of Infection and Factor V Leiden Mutation Post-Partum Yumurtalık Ven Trombozu: Enfeksiyon ve Faktör V Leiden Mutasyonunun Birleşik Etkisi